Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CEM63164.1CobW/P47K family protein. (296 aa)    
Predicted Functional Partners:
folE
GTP cyclohydrolase FolE2; Converts GTP to 7,8-dihydroneopterin triphosphate.
  
  
 0.755
CEM61311.1
C4-type zinc finger protein, DksA/TraR family.
  
  
 0.717
adh-2
NADP-dependent isopropanol dehydrogenase.
 
     0.698
rpmB
50S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
  
  
 0.694
map
Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
    
 
 0.693
troA
Periplasmic zinc-binding protein TroA; Belongs to the bacterial solute-binding protein 9 family.
  
  
 0.671
CEM61640.1
Uncharacterized periplasmic metal-binding protein TP_0034; Belongs to the bacterial solute-binding protein 9 family.
  
  
 0.671
CEM61729.1
Conserved membrane hypothetical protein; Homologs of previously reported genes of unknown function.
 
     0.602
rpmG
50S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.
  
  
 0.585
hbpB
Hemin-binding protein B.
  
  
 0.517
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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