Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
adh-2NADP-dependent isopropanol dehydrogenase. (351 aa)    
Predicted Functional Partners:
CEM63164.1
CobW/P47K family protein.
 
     0.698
adhE
Fused acetaldehyde-CoA dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.579
nifJ
Pyruvate-flavodoxin oxidoreductase.
  
  
 0.537
ydbK
Putative 2-oxoacid-flavodoxin fused oxidoreductase:conserved protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.536
CEM61784.1
Diguanylate cyclase (GGDEF) domain protein (fragment).
  
  
 0.435
CEM63166.1
Transcriptional regulator, DeoR family.
       0.432
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
  
  
 0.430
CEM61478.1
Pyridine nucleotide-disulfide oxidoreductase (modular protein).
  
  
 0.427
CEM60782.1
Mutator mutT protein; Belongs to the Nudix hydrolase family.
    
 0.407
CEM61966.1
Rubredoxin.
  
 
 0.405
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
Server load: medium (46%) [HD]