Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
yrbEUncharacterized oxidoreductase YrbE. (336 aa)    
Predicted Functional Partners:
iolE
Inosose dehydratase.
 
 
 0.982
IolG
Oxidoreductase, NAD-binding domain protein.
  
  
 
0.921
CEM63167.1
Myo-inositol catabolism protein IolB.
 
  
 0.897
iolC
5-dehydro-2-deoxygluconokinase.
 
  
 0.895
iolD
3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; Belongs to the TPP enzyme family.
 
  
 0.845
CEM63169.1
Ketose-bisphosphate aldolase.
  
  
 0.682
ydbK
Putative 2-oxoacid-flavodoxin fused oxidoreductase:conserved protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.412
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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