Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AmrSConserved hypothetical protein; Homologs of previously reported genes of unknown function. (284 aa)    
Predicted Functional Partners:
AmrA
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
     0.823
CEM63182.1
Hypothetical protein; No homology to any previously reported sequences.
       0.773
pflB
Pyruvate formate lyase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.707
adhE
Fused acetaldehyde-CoA dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
  
 0.638
ydbK
Putative 2-oxoacid-flavodoxin fused oxidoreductase:conserved protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.575
nifJ
Pyruvate-flavodoxin oxidoreductase.
     
 0.542
CEM63181.1
DEAD/DEAH box helicase; Belongs to the DEAD box helicase family.
       0.537
CEM61086.1
Alcohol dehydrogenase, iron-dependent.
  
  
 0.405
adh
NADPH-dependent butanol dehydrogenase.
  
  
 0.405
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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