STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pcnBPoly(A) polymerase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (399 aa)    
Predicted Functional Partners:
CEM63198.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.592
ribD
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
    0.586
metG
Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
 
 
 0.576
pnp
Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
 
 
 0.575
CEM63071.1
PP-loop family protein; Belongs to the TtcA family.
 
  
 0.545
CEM62499.1
Helicase C-terminal domain protein.
 
 
 0.542
CEM60452.1
Peptidyl-prolyl cis-trans isomerase.
  
   0.488
CEM63019.1
RNB-like protein.
 
 
 0.471
CEM60662.1
Serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family.
 
   
 0.464
folK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridinediphosphokinase.
  
    0.432
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.