Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
trxAThioredoxin; Belongs to the thioredoxin family. (105 aa)    
Predicted Functional Partners:
groL
Cpn60 chaperonin GroEL, large subunit of GroESL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
 
 
 0.890
nrdA
Ribonucleoside-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 
 0.866
CEM61478.1
Pyridine nucleotide-disulfide oxidoreductase (modular protein).
     
 0.854
CEM61005.1
Pyridine nucleotide-disulfide oxidoreductase (fragment).
  
 
 0.816
trxB
Thioredoxin reductase.
 
 
 0.810
CEM60437.1
Phosphoribulokinase/uridine kinase family protein.
   
 
 0.737
ahpC
Alkyl hydroperoxide reductase, C22 subunit; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
 
 0.735
CEM60841.1
Pyridine nucleotide-disulfide oxidoreductase (fragment).
  
 
 0.721
CEM60842.1
Pyridine nucleotide-disulfide oxidoreductase (fragment).
  
 
 0.711
CEM61749.1
Pyridine nucleotide-disulfide oxidoreductase.
  
 
 0.711
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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