STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pncBNicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (476 aa)    
Predicted Functional Partners:
nadD
Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.941
CEM63224.1
Competence/damage-inducible domain protein CinA; Belongs to the CinA family.
  
 
 0.929
deoD
Purine nucleoside phosphorylase DeoD-type.
     
 0.915
nadN
Putative 5'-nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the 5'-nucleotidase family.
    
 0.904
surE
5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.902
CEM61651.1
Bacterial capsule synthesis protein.
  
    0.764
nifJ
Pyruvate-flavodoxin oxidoreductase.
     
 0.732
nadE
NAD+ synthase; Belongs to the NAD synthetase family.
 
  
 0.720
ydbK
Putative 2-oxoacid-flavodoxin fused oxidoreductase:conserved protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.642
asnS
Asparaginyl tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.561
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.