Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
mtlAPTS system mannitol-specific EIICBA component (Includes: Mannitol permease IIC component; Mannitol-specific phosphotransferase enzyme IIB component; Mannitol-specific phosphotransferase enzyme IIA component). (611 aa)    
Predicted Functional Partners:
fruA-2
Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; PTS system fructose-specific EIIABC component (Includes: Fructose-specific phosphotransferase enzyme IIA component; Fructose-specific phosphotransferase enzyme IIB component; Fructose permease IIC component).
 
  
0.997
fruA
PTS system fructose-specific EIIABC component.
  
  
 0.996
ptsH
Phosphocarrier protein HPr.
   
 0.986
ptsH-2
Phosphocarrier protein HPr.
   
 0.986
ptsH-3
Phosphocarrier protein HPr.
   
 0.986
CEM63462.1
Mannitol dehydrogenase domain protein.
  
  
 0.982
CEM60646.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
  
 0.942
fruK
1-phosphofructokinase; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.933
yggP
Putative dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
   
 0.909
CEM62560.1
PTS system, beta-glucoside-specific, IIABC component.
 
   
 0.897
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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