Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CEM63416.1DNA topoisomerase (fragment). (448 aa)    
Predicted Functional Partners:
CEM63415.1
TraG/TraD/VirD4 bacterial conjugation protein (fragment).
   
 0.980
recQ
ATP-dependent DNA helicase RecQ.
 
 0.959
CEM61386.1
ATP-dependent DNA helicase, RecQ family.
 
 0.907
CEM63421.1
Helicase (fragment).
 
 
 0.898
recA
DNA strand exchange and recombination protein with protease and nuclease activity; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.855
nifJ
Pyruvate-flavodoxin oxidoreductase.
  
   0.809
CEM63422.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
     0.805
CEM63438.1
AAA-like domain protein.
 
  
 0.791
CEM63440.1
Conserved membrane hypothetical protein; Homologs of previously reported genes of unknown function.
 
     0.781
ydbK
Putative 2-oxoacid-flavodoxin fused oxidoreductase:conserved protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
   0.748
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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