Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CEM63422.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (1114 aa)    
Predicted Functional Partners:
CEM63421.1
Helicase (fragment).
   
 0.995
CEM62286.1
Type I restriction modification DNA specificity domain protein.
  
 
 0.863
CEM63415.1
TraG/TraD/VirD4 bacterial conjugation protein (fragment).
 
   
 0.834
CEM63438.1
AAA-like domain protein.
 
     0.824
CEM63440.1
Conserved membrane hypothetical protein; Homologs of previously reported genes of unknown function.
 
     0.810
CEM63416.1
DNA topoisomerase (fragment).
 
     0.805
hsdR
Putative Type I site-specific deoxyribonuclease; Subunit R is required for both nuclease and ATPase activities, but not for modification.
  
  
 0.697
CEM63420.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
     0.579
CEM62283.1
Virulence protein.
  
    0.569
CEM63423.1
Cro/C1-type HTH DNA-binding domain protein.
       0.566
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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