Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
adhEFused acetaldehyde-CoA dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (884 aa)    
Predicted Functional Partners:
ydbK
Putative 2-oxoacid-flavodoxin fused oxidoreductase:conserved protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 0.994
nifJ
Pyruvate-flavodoxin oxidoreductase.
  
 0.993
pflB
Pyruvate formate lyase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.965
bcd
Acyl-CoA dehydrogenase, short-chain specific.
  
 
 0.960
atoB
acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; carrier; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.956
pta
Phosphate acetyltransferase.
  
 
 0.942
ywdH
Putative aldehyde dehydrogenase YwdH; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the aldehyde dehydrogenase family.
  
 0.931
bdhA
NADH-dependent butanol dehydrogenase A.
 
 
0.926
CEM62108.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
  
 0.868
iolA
Methylmalonate semialdehyde dehydrogenase (acylating) 2.
  
 0.863
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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