Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
CEM63449.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (333 aa)    
Predicted Functional Partners:
CEM63448.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.773
CEM60904.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
     0.674
CEM63450.1
Hypothetical protein; No homology to any previously reported sequences.
       0.550
proS
Proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...]
       0.539
CEM63452.1
Conserved exported hypothetical protein; Homologs of previously reported genes of unknown function.
       0.519
CEM61166.1
RNA methyltransferase, TrmH family; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
 
   
 0.510
CEM60867.1
Divergent polysaccharide deacetylase.
  
     0.456
CEM63447.1
Hypothetical protein; No homology to any previously reported sequences.
       0.405
Your Current Organism:
Treponema phagedenis
NCBI taxonomy Id: 162
Other names: T. phagedenis
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