STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRN76935.1Pyruvate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component. (469 aa)    
Predicted Functional Partners:
KRN76934.1
Dihydrolipoyllysine-residue acetyltransferase.
 0.999
KRN76932.1
Hypothetical protein.
 
 0.998
KRN76933.1
Pyruvate dehydrogenase (acetyl-transferring).
 0.998
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.949
KRN77777.1
L-glutamine synthetase.
  
 
 0.933
KRN76931.1
Lipoate-protein ligase.
 
 
 0.912
KRN77068.1
Thiol-disulfide isomerase and thioredoxin.
  
 0.870
purQ
Phosphoribosylformylglycinamidine synthase domain-containing protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL an [...]
  
 
  0.846
KRN77801.1
Lipoate-protein ligase A.
 
 
 0.767
KRN76676.1
Ribose-phosphate pyrophosphokinase.
   
 0.611
Your Current Organism:
Weissella minor
NCBI taxonomy Id: 1620
Other names: ATCC 35412, BCRC 14049, CCRC 14049, CCRC:14049, CCUG 30668, CECT 572, CIP 102978, DSM 20014, LMG 9847, LMG:9847, Lactobacillus minor, Lactobacillus viridescens subsp. minor, NCIMB 701973, W. minor, strain 3
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