node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KRN76029.1 | KRN76328.1 | IV67_GL001079 | IV67_GL000904 | Macrolide-efflux protein. | ACP S-malonyltransferase. | 0.924 |
KRN76029.1 | KRN76330.1 | IV67_GL001079 | IV67_GL000906 | Macrolide-efflux protein. | 3-oxoacyl-(acyl-carrier-protein) synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | 0.890 |
KRN76029.1 | KRN76840.1 | IV67_GL001079 | IV67_GL000349 | Macrolide-efflux protein. | Alpha beta superfamily hydrolase acyltransferase. | 0.868 |
KRN76029.1 | KRN76936.1 | IV67_GL001079 | IV67_GL000446 | Macrolide-efflux protein. | Alpha beta fold family hydrolase. | 0.868 |
KRN76029.1 | acpP | IV67_GL001079 | IV67_GL000876 | Macrolide-efflux protein. | Hypothetical protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | 0.985 |
KRN76029.1 | acpP-2 | IV67_GL001079 | IV67_GL000902 | Macrolide-efflux protein. | Hypothetical protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | 0.985 |
KRN76029.1 | dltC | IV67_GL001079 | IV67_GL000406 | Macrolide-efflux protein. | Hypothetical protein; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. | 0.985 |
KRN76029.1 | fabH | IV67_GL001079 | IV67_GL000901 | Macrolide-efflux protein. | 3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. | 0.893 |
KRN76029.1 | menE | IV67_GL001079 | IV67_GL001029 | Macrolide-efflux protein. | Acyl-coa synthetase (amp-forming) amp-acid ligase ii; Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA); Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily. | 0.975 |
KRN76029.1 | menH | IV67_GL001079 | IV67_GL001509 | Macrolide-efflux protein. | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Catalyzes a proton abstraction reaction that results in 2,5- elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6- hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). | 0.887 |
KRN76328.1 | KRN76029.1 | IV67_GL000904 | IV67_GL001079 | ACP S-malonyltransferase. | Macrolide-efflux protein. | 0.924 |
KRN76328.1 | KRN76330.1 | IV67_GL000904 | IV67_GL000906 | ACP S-malonyltransferase. | 3-oxoacyl-(acyl-carrier-protein) synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | 0.999 |
KRN76328.1 | acpP | IV67_GL000904 | IV67_GL000876 | ACP S-malonyltransferase. | Hypothetical protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | 0.954 |
KRN76328.1 | acpP-2 | IV67_GL000904 | IV67_GL000902 | ACP S-malonyltransferase. | Hypothetical protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | 0.988 |
KRN76328.1 | dltC | IV67_GL000904 | IV67_GL000406 | ACP S-malonyltransferase. | Hypothetical protein; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. | 0.945 |
KRN76328.1 | fabH | IV67_GL000904 | IV67_GL000901 | ACP S-malonyltransferase. | 3-oxoacyl-[acyl-carrier-protein] synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. | 0.998 |
KRN76328.1 | menE | IV67_GL000904 | IV67_GL001029 | ACP S-malonyltransferase. | Acyl-coa synthetase (amp-forming) amp-acid ligase ii; Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA); Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily. | 0.667 |
KRN76330.1 | KRN76029.1 | IV67_GL000906 | IV67_GL001079 | 3-oxoacyl-(acyl-carrier-protein) synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | Macrolide-efflux protein. | 0.890 |
KRN76330.1 | KRN76328.1 | IV67_GL000906 | IV67_GL000904 | 3-oxoacyl-(acyl-carrier-protein) synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | ACP S-malonyltransferase. | 0.999 |
KRN76330.1 | acpP | IV67_GL000906 | IV67_GL000876 | 3-oxoacyl-(acyl-carrier-protein) synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. | Hypothetical protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | 0.911 |