STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
AKM84954.1Putative 2-deoxycytidine 5-triphosphate deaminase, dCTP deaminase. (381 aa)    
Predicted Functional Partners:
AKM84544.1
Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut, dUTP pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
    
 0.985
AKM84911.1
Nucleoside diphosphate kinase, nucleoside-diphosphate kinase.
  
 
 0.985
pyrG
CTP synthase, CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
 
 0.927
AKM84546.1
Thymidylate synthase complementing protein ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.
    
 0.868
AKM84811.1
Uridine kinase, uridine kinase; Belongs to the uridine kinase family.
    
 0.772
AKM84461.1
7,8-dihydro-8-oxoguanine triphosphatase.
    
  0.676
AKM84509.1
Hydrolase.
    
  0.676
AKM84595.1
Hypothetical protein.
    
  0.676
AKM85003.1
Hypothetical protein.
 
     0.665
topA
Topoisomerase I, DNA topoisomerase I protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken stran [...]
       0.629
Your Current Organism:
candidate division Kazan bacterium GW2011GWA15015
NCBI taxonomy Id: 1620412
Other names: bacterium GW2011_GWA1_50_15, c. division Kazan bacterium GW2011_GWA1_50_15, candidate division Kazan bacterium GW2011_GWA1_50_15
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