STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMM39967.1Peptidase A31, hydrogen uptake protein. (153 aa)    
Predicted Functional Partners:
AMM39968.1
Iron hydrogenase.
 
 
 0.975
AMM39969.1
Quinone-reactive Ni/Fe-hydrogenase small chain.
 
 
 0.966
mvhG
Methyl viologen-reducing hydrogenase.
  
 
 0.678
AMM39955.1
Hydrogenase expression/formation protein HypE.
 
   
 0.671
AMM39956.1
Hydrogenase formation HypD protein; Belongs to the HypD family.
 
   
 0.670
AMM39963.1
HAD family hydrolase; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
   
 0.660
hdrB
Heterodisulfide reductase, subunit B.
  
 
 0.566
hdrB-2
Heterodisulfide reductase, subunit B.
  
 
 0.566
hypA
Hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.537
hdrC-4
Heterodisulfide reductase, subunit C.
  
 
 0.515
Your Current Organism:
Desulfofervidus auxilii
NCBI taxonomy Id: 1621989
Other names: C. Desulfofervidus auxilii, Candidatus Desulfofervidus auxilii, delta proteobacterium HotSeep1
Server load: low (30%) [HD]