STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMM40575.1Branched chain amino acid ABC transporter substrate-binding protein. (378 aa)    
Predicted Functional Partners:
AMM41583.1
Membrane protein containing ATP-binding region, ATPase-like protein.
  
 0.829
AMM42126.1
Conserved hypothetical protein, secreted.
    
 0.816
grpE
GrpE nucleotide exchange factor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...]
  
    0.813
AMM40799.1
Multi-sensor hybrid histidine kinase.
  
 0.811
AMM40942.1
Branched-chain amino acid ABC transporter substrate-binding protein.
  
  
  0.807
AMM40574.1
Histone deacetylase/AcuC/AphA family protein.
       0.781
hrcA
Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
       0.779
AMM40579.1
Metal-dependent phosphohydrolase, HD region, subdomain protein.
  
 0.749
AMM41276.1
Stage II sporulation protein E.
 
  
  0.728
AMM41002.1
Multi-sensor hybrid histidine kinase.
    
 0.725
Your Current Organism:
Desulfofervidus auxilii
NCBI taxonomy Id: 1621989
Other names: C. Desulfofervidus auxilii, Candidatus Desulfofervidus auxilii, delta proteobacterium HotSeep1
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