node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMM40574.1 | AMM40575.1 | HS1_000770 | HS1_000771 | Histone deacetylase/AcuC/AphA family protein. | Branched chain amino acid ABC transporter substrate-binding protein. | 0.781 |
AMM40574.1 | AMM41583.1 | HS1_000770 | HS1_001789 | Histone deacetylase/AcuC/AphA family protein. | Membrane protein containing ATP-binding region, ATPase-like protein. | 0.455 |
AMM40574.1 | grpE | HS1_000770 | HS1_000772 | Histone deacetylase/AcuC/AphA family protein. | GrpE nucleotide exchange factor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.773 |
AMM40574.1 | hrcA | HS1_000770 | HS1_000773 | Histone deacetylase/AcuC/AphA family protein. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.768 |
AMM40575.1 | AMM40574.1 | HS1_000771 | HS1_000770 | Branched chain amino acid ABC transporter substrate-binding protein. | Histone deacetylase/AcuC/AphA family protein. | 0.781 |
AMM40575.1 | AMM40579.1 | HS1_000771 | HS1_000775 | Branched chain amino acid ABC transporter substrate-binding protein. | Metal-dependent phosphohydrolase, HD region, subdomain protein. | 0.749 |
AMM40575.1 | AMM40799.1 | HS1_000771 | HS1_000995 | Branched chain amino acid ABC transporter substrate-binding protein. | Multi-sensor hybrid histidine kinase. | 0.811 |
AMM40575.1 | AMM40942.1 | HS1_000771 | HS1_001138 | Branched chain amino acid ABC transporter substrate-binding protein. | Branched-chain amino acid ABC transporter substrate-binding protein. | 0.807 |
AMM40575.1 | AMM41002.1 | HS1_000771 | HS1_001198 | Branched chain amino acid ABC transporter substrate-binding protein. | Multi-sensor hybrid histidine kinase. | 0.725 |
AMM40575.1 | AMM41276.1 | HS1_000771 | HS1_001477 | Branched chain amino acid ABC transporter substrate-binding protein. | Stage II sporulation protein E. | 0.728 |
AMM40575.1 | AMM41583.1 | HS1_000771 | HS1_001789 | Branched chain amino acid ABC transporter substrate-binding protein. | Membrane protein containing ATP-binding region, ATPase-like protein. | 0.829 |
AMM40575.1 | AMM42126.1 | HS1_000771 | HS1_002344 | Branched chain amino acid ABC transporter substrate-binding protein. | Conserved hypothetical protein, secreted. | 0.816 |
AMM40575.1 | grpE | HS1_000771 | HS1_000772 | Branched chain amino acid ABC transporter substrate-binding protein. | GrpE nucleotide exchange factor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...] | 0.813 |
AMM40575.1 | hrcA | HS1_000771 | HS1_000773 | Branched chain amino acid ABC transporter substrate-binding protein. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.779 |
AMM40579.1 | AMM40575.1 | HS1_000775 | HS1_000771 | Metal-dependent phosphohydrolase, HD region, subdomain protein. | Branched chain amino acid ABC transporter substrate-binding protein. | 0.749 |
AMM40579.1 | AMM40799.1 | HS1_000775 | HS1_000995 | Metal-dependent phosphohydrolase, HD region, subdomain protein. | Multi-sensor hybrid histidine kinase. | 0.998 |
AMM40579.1 | AMM41002.1 | HS1_000775 | HS1_001198 | Metal-dependent phosphohydrolase, HD region, subdomain protein. | Multi-sensor hybrid histidine kinase. | 0.974 |
AMM40579.1 | AMM41276.1 | HS1_000775 | HS1_001477 | Metal-dependent phosphohydrolase, HD region, subdomain protein. | Stage II sporulation protein E. | 0.957 |
AMM40579.1 | AMM41583.1 | HS1_000775 | HS1_001789 | Metal-dependent phosphohydrolase, HD region, subdomain protein. | Membrane protein containing ATP-binding region, ATPase-like protein. | 0.998 |
AMM40579.1 | AMM42126.1 | HS1_000775 | HS1_002344 | Metal-dependent phosphohydrolase, HD region, subdomain protein. | Conserved hypothetical protein, secreted. | 0.704 |