STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AMM40816.1Conserved hypothetical protein, secreted. (305 aa)    
Predicted Functional Partners:
AMM40815.1
Secreted protein.
       0.773
AMM40814.1
Conjugal transfer protein TraN.
       0.771
AMM40813.1
Secreted protein.
       0.752
AMM40812.1
Secreted protein.
       0.711
AMM40810.1
Conjugal transfer protein TraU.
     
 0.688
AMM40811.1
Hypothetical protein.
       0.686
AMM39876.1
General secretion pathway protein K.
  
 
 0.610
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
  
 0.592
AMM39929.1
Type II secretory protein GspE.
  
 0.555
AMM39871.1
Type II secretory protein GspE; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.
   
 0.539
Your Current Organism:
Desulfofervidus auxilii
NCBI taxonomy Id: 1621989
Other names: C. Desulfofervidus auxilii, Candidatus Desulfofervidus auxilii, delta proteobacterium HotSeep1
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