node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMM41058.1 | AMM41498.1 | HS1_001254 | HS1_001704 | 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Arabinose 5-phosphate isomerase KdsD; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.873 |
AMM41058.1 | AMM41703.1 | HS1_001254 | HS1_001909 | 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase. | 0.624 |
AMM41058.1 | kdsA | HS1_001254 | HS1_001908 | 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | 0.780 |
AMM41058.1 | kdsB | HS1_001254 | HS1_000255 | 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.915 |
AMM41058.1 | lpxK | HS1_001254 | HS1_001256 | 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | Tetraacyldisaccharide-1-P 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.998 |
AMM41218.1 | AMM41498.1 | HS1_001416 | HS1_001704 | Iron-sulfur cluster assembly protein HesB. | Arabinose 5-phosphate isomerase KdsD; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.862 |
AMM41218.1 | pfkA | HS1_001416 | HS1_001706 | Iron-sulfur cluster assembly protein HesB. | Diphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. | 0.589 |
AMM41498.1 | AMM41058.1 | HS1_001704 | HS1_001254 | Arabinose 5-phosphate isomerase KdsD; Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.873 |
AMM41498.1 | AMM41218.1 | HS1_001704 | HS1_001416 | Arabinose 5-phosphate isomerase KdsD; Belongs to the SIS family. GutQ/KpsF subfamily. | Iron-sulfur cluster assembly protein HesB. | 0.862 |
AMM41498.1 | AMM41499.1 | HS1_001704 | HS1_001705 | Arabinose 5-phosphate isomerase KdsD; Belongs to the SIS family. GutQ/KpsF subfamily. | Dihydrodipicolinate synthase; Belongs to the DapA family. | 0.917 |
AMM41498.1 | AMM41703.1 | HS1_001704 | HS1_001909 | Arabinose 5-phosphate isomerase KdsD; Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase. | 0.995 |
AMM41498.1 | guaA | HS1_001704 | HS1_000145 | Arabinose 5-phosphate isomerase KdsD; Belongs to the SIS family. GutQ/KpsF subfamily. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.917 |
AMM41498.1 | kdsA | HS1_001704 | HS1_001908 | Arabinose 5-phosphate isomerase KdsD; Belongs to the SIS family. GutQ/KpsF subfamily. | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | 0.973 |
AMM41498.1 | kdsB | HS1_001704 | HS1_000255 | Arabinose 5-phosphate isomerase KdsD; Belongs to the SIS family. GutQ/KpsF subfamily. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.893 |
AMM41498.1 | lpxK | HS1_001704 | HS1_001256 | Arabinose 5-phosphate isomerase KdsD; Belongs to the SIS family. GutQ/KpsF subfamily. | Tetraacyldisaccharide-1-P 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.864 |
AMM41498.1 | pfkA | HS1_001704 | HS1_001706 | Arabinose 5-phosphate isomerase KdsD; Belongs to the SIS family. GutQ/KpsF subfamily. | Diphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. | 0.917 |
AMM41498.1 | purF | HS1_001704 | HS1_001703 | Arabinose 5-phosphate isomerase KdsD; Belongs to the SIS family. GutQ/KpsF subfamily. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.844 |
AMM41499.1 | AMM41498.1 | HS1_001705 | HS1_001704 | Dihydrodipicolinate synthase; Belongs to the DapA family. | Arabinose 5-phosphate isomerase KdsD; Belongs to the SIS family. GutQ/KpsF subfamily. | 0.917 |
AMM41499.1 | guaA | HS1_001705 | HS1_000145 | Dihydrodipicolinate synthase; Belongs to the DapA family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.461 |
AMM41499.1 | pfkA | HS1_001705 | HS1_001706 | Dihydrodipicolinate synthase; Belongs to the DapA family. | Diphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily. | 0.718 |