node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMM41063.1 | AMM41874.1 | HS1_001259 | HS1_002086 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Haloacid dehalogenase, type II. | 0.568 |
AMM41063.1 | glyA | HS1_001259 | HS1_000512 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.563 |
AMM41063.1 | guaA | HS1_001259 | HS1_000145 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.644 |
AMM41063.1 | nadD | HS1_001259 | HS1_001536 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.676 |
AMM41194.1 | AMM41233.1 | HS1_001391 | HS1_001431 | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.575 |
AMM41194.1 | AMM41280.1 | HS1_001391 | HS1_001481 | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Competence damage-inducible protein A; Belongs to the CinA family. | 0.884 |
AMM41194.1 | AMM41874.1 | HS1_001391 | HS1_002086 | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Haloacid dehalogenase, type II. | 0.582 |
AMM41194.1 | nadD | HS1_001391 | HS1_001536 | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.711 |
AMM41233.1 | AMM41194.1 | HS1_001431 | HS1_001391 | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | 0.575 |
AMM41233.1 | AMM41490.1 | HS1_001431 | HS1_001696 | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.445 |
AMM41233.1 | AMM41874.1 | HS1_001431 | HS1_002086 | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Haloacid dehalogenase, type II. | 0.900 |
AMM41233.1 | guaA | HS1_001431 | HS1_000145 | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.631 |
AMM41233.1 | nadD | HS1_001431 | HS1_001536 | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.727 |
AMM41280.1 | AMM41194.1 | HS1_001481 | HS1_001391 | Competence damage-inducible protein A; Belongs to the CinA family. | Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. | 0.884 |
AMM41280.1 | AMM41874.1 | HS1_001481 | HS1_002086 | Competence damage-inducible protein A; Belongs to the CinA family. | Haloacid dehalogenase, type II. | 0.693 |
AMM41280.1 | nadD | HS1_001481 | HS1_001536 | Competence damage-inducible protein A; Belongs to the CinA family. | Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.926 |
AMM41490.1 | AMM41233.1 | HS1_001696 | HS1_001431 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 5-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.445 |
AMM41490.1 | AMM41874.1 | HS1_001696 | HS1_002086 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Haloacid dehalogenase, type II. | 0.588 |
AMM41490.1 | glyA | HS1_001696 | HS1_000512 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.833 |
AMM41874.1 | AMM41063.1 | HS1_002086 | HS1_001259 | Haloacid dehalogenase, type II. | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.568 |