STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kbl2-amino-3-ketobutyrate CoA ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (397 aa)    
Predicted Functional Partners:
gcvP
Glycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
 
 0.937
AMC09910.1
8-amino-7-oxononanoate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.921
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.919
AMC09949.1
Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.915
AMC11593.1
NAD-dependent epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.762
AMC11952.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.726
AMC11361.1
DNA helicase UvrD; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the helicase family. UvrD subfamily.
     
 0.719
AMC11726.1
ACP S-malonyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.671
AMC11443.1
3-oxoacyl-ACP synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
    
 0.607
AMC11360.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.551
Your Current Organism:
Lutibacter profundi
NCBI taxonomy Id: 1622118
Other names: DSM 100437, JCM 30586, L. profundi, Lutibacter profundi Le Moine Bauer et al. 2016, Lutibacter sp. LP1, strain LP1
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.