STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ctaDCytochrome C oxidase subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (587 aa)    
Predicted Functional Partners:
KIC57486.1
Cytochrome B561; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
KIC57487.1
Cystathionine beta-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.999
KIC57488.1
Ubiquinol-cytochrome C reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.999
KIC57489.1
Ubiquinol-cytochrome c reductase cytochrome b subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.999
KIC57492.1
Cytochrome c oxidase subunit IV; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.999
coxB
Cytochrome C oxidase subunit II; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
ctaB
Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
 
 0.990
KIC58262.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.966
atpB
ATP synthase F0F1 subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family.
 
 
 0.800
rpsL
30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
  
  
 0.765
Your Current Organism:
Microbacterium hominis
NCBI taxonomy Id: 162426
Other names: CIP 105731, DSM 12509, IFO 15708, JCM 12413, LCDC 84-209, M. hominis, NBRC 15708, VKM Ac-2081
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.