STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
stpMultidrug resistance protein stp. (519 aa)    
Predicted Functional Partners:
nrdZ
Ribonucleoside-diphosphate reductase NrdZ; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
   
  0.922
emrA
Multidrug export protein EmrA.
 
 0.898
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
  0.897
tdk
Thymidine kinase.
     
 0.896
nrdB
Ribonucleoside-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
   
 
  0.851
folP
Dihydropteroate synthase.
 
   
 0.637
mdtL_2
Multidrug resistance protein MdtL.
  
   
 0.616
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
  
 0.596
Cva_00917
Blue-light-activated protein.
  
  
 0.585
Cva_01417
Cyclic nucleotide-binding domain protein.
     
 0.585
Your Current Organism:
Caedimonas varicaedens
NCBI taxonomy Id: 1629334
Other names: ATCC 30637, ATCC 50168 [[Caedibacter caryophilus]], C. varicaedens, Caedibacter caryophila, Caedibacter caryophilus, Caedibacter macronucleorum, Caedibacter varicaedens, strain 221 [[Caedibacter caryophilus]], strain 7
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