KJS00118.1 protein (Desulfobulbaceae bacterium BRHc16a)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Cooccurrence

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[Homology]

Score

KJS00118.1

Pyruvate carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1228 aa)

Predicted Functional Partners:

KJS00117.1

0.968

KJS01966.1

0.926

KJS00578.1

0.896

KJS00978.1

0.890

KJS00579.1

0.885

KJR97304.1

0.884

gltB

0.870

KJS00114.1

0.860

KJS00113.1

0.854

KJS03517.1

0.838

Your Current Organism:

Desulfobulbaceae bacterium BRHc16a

NCBI taxonomy Id: 1629713
Other names: D. bacterium BRH_c16a, Desulfobulbaceae bacterium BRH_c16a

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KJR97304.1	KJS00113.1	VR65_25640	VR65_14545	Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.897
KJR97304.1	KJS00114.1	VR65_25640	VR65_14550	Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.887
KJR97304.1	KJS00117.1	VR65_25640	VR65_14565	Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.663
KJR97304.1	KJS00118.1	VR65_25640	VR65_14570	Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.884
KJR97304.1	KJS00978.1	VR65_25640	VR65_11300	Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
KJR97304.1	KJS01966.1	VR65_25640	VR65_07210	Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.882
KJR97304.1	KJS03517.1	VR65_25640	VR65_00690	Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family.	0.982
KJR97304.1	gltB	VR65_25640	VR65_22435	Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.926
KJS00113.1	KJR97304.1	VR65_14545	VR65_25640	methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.897
KJS00113.1	KJS00114.1	VR65_14545	VR65_14550	methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
KJS00113.1	KJS00117.1	VR65_14545	VR65_14565	methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.843
KJS00113.1	KJS00118.1	VR65_14545	VR65_14570	methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.854
KJS00113.1	KJS00978.1	VR65_14545	VR65_11300	methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.916
KJS00113.1	KJS01966.1	VR65_14545	VR65_07210	methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.897
KJS00113.1	gltB	VR65_14545	VR65_22435	methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.860
KJS00114.1	KJR97304.1	VR65_14550	VR65_25640	acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate-flavodoxin oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.887
KJS00114.1	KJS00113.1	VR65_14550	VR65_14545	acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
KJS00114.1	KJS00117.1	VR65_14550	VR65_14565	acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.886
KJS00114.1	KJS00118.1	VR65_14550	VR65_14570	acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Pyruvate carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.860
KJS00114.1	KJS00578.1	VR65_14550	VR65_12240	acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Allophanate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.958

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Network Stats

number of nodes:

11

number of edges:

46

average node degree:

8.36

avg. local clustering coefficient:

0.982

expected number of edges:

24

PPI enrichment p-value:

5.63e-05

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

9 of 109

1.44

2.4

1.70e-09

GO:0044249

Cellular biosynthetic process

10 of 634

0.72

0.67

2.23e-05

GO:1901576

Organic substance biosynthetic process

10 of 655

0.71

0.65

2.85e-05

GO:0044238

Primary metabolic process

11 of 1231

0.48

0.4

0.00048

GO:0071704

Organic substance metabolic process

11 of 1519

0.38

0.32

0.0038

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019843

rRNA binding

9 of 45

1.83

4.27

5.90e-13

GO:0003735

Structural constituent of ribosome

9 of 57

1.72

3.78

2.04e-12

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

9 of 61

1.69

3.72

1.11e-12

GO:0015935

Small ribosomal subunit

3 of 10

2.0

1.97

0.00010

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:195

rRNA-binding

6 of 9

2.35

4.97

5.83e-11

CL:162

rRNA-binding

8 of 28

1.98

4.56

4.61e-12

CL:156

Structural constituent of ribosome

9 of 62

1.69

3.59

4.61e-12

CL:1841

Mixed, incl. Fatty acyl-CoA reductase, and Steroid metabolic process

2 of 7

1.98

0.98

0.0136

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

9 of 60

1.7

3.75

1.04e-12

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0015935

Small ribosomal subunit

6 of 16

2.1

3.93

2.42e-09

GOCC:0022627

Cytosolic small ribosomal subunit

5 of 15

2.05

3.35

5.14e-08

GOCC:0043229

Intracellular organelle

10 of 323

1.02

1.25

2.07e-08

GOCC:0005622

Intracellular

11 of 1297

0.45

0.39

0.00024

GOCC:0005737

Cytoplasm

8 of 918

0.47

0.32

0.0230

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0699

rRNA-binding

9 of 42

1.86

4.55

9.99e-14

KW-0689

Ribosomal protein

9 of 59

1.71

3.8

8.02e-13

KW-0820

tRNA-binding

2 of 15

1.65

0.68

0.0458

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