STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spoIIABATPase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. (148 aa)    
Predicted Functional Partners:
KJS18502.1
Anti-sigma F factor antagonist; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.997
KJS18500.1
Sporulation sigma factor SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
 
 0.982
KJS14689.1
Sporulation sigma factor SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
 
 0.924
KJS14690.1
Sporulation sigma factor SigE; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
 
 0.873
KJS14691.1
Hypothetical protein; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family.
  
  
 0.871
KJS15143.1
Stage III sporulation protein D; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.862
KJS15844.1
RNA polymerase sigma 70; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
 
 0.857
KJS17012.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
  
 0.841
KJS18522.1
Stage V sporulation protein T; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.831
KJS15062.1
Stage V sporulation protein T; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.826
Your Current Organism:
Peptococcaceae bacterium BRHc4b
NCBI taxonomy Id: 1629717
Other names: P. bacterium BRH_c4b, Peptococcaceae bacterium BRH_c4b
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.