STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa)    
Predicted Functional Partners:
SEI68041.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
 
 0.991
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.954
SEJ20750.1
Fructose-bisphosphate aldolase, class II.
  
 
 0.893
SEI54720.1
Transaldolase.
  
 
 0.787
SEJ04734.1
Fructose-1-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
     
 0.762
pfp
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
  
  
 
0.757
guaA
GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
   
  
 0.754
SEI95051.1
Mannose-6-phosphate isomerase, type 1.
     
 0.747
SEI59340.1
Fructokinase.
   
 
  0.740
fhs
Formate-tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family.
    
 
 0.673
Your Current Organism:
Kandleria vitulina
NCBI taxonomy Id: 1630
Other names: ATCC 27783, CCUG 32236, CIP 103154, DSM 20405, K. vitulina, LMG 18931, LMG:18931, Lactobacillus vitulinus, NRRL B-14854
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