STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEI88900.1Glycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (318 aa)    
Predicted Functional Partners:
SEI68041.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.929
SEJ27221.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
    
  0.862
SEI83002.1
Acetaldehyde dehydrogenase /alcohol dehydrogenase AdhE; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.853
SEJ32457.1
NAD(P)-dependent iron-only hydrogenase diaphorase component flavoprotein.
   
 
 0.828
SEI58763.1
L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
   
 
 0.820
SEI58046.1
acetyl-CoA carboxylase biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
    
  0.807
SEJ32487.1
NAD(P)-dependent iron-only hydrogenase catalytic subunit.
     
 0.761
SEI88974.1
Exonuclease SbcC.
 
    0.754
sbcD
Exodeoxyribonuclease I subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
 
    0.744
SEI88923.1
Acetyltransferase (GNAT) domain-containing protein.
       0.701
Your Current Organism:
Kandleria vitulina
NCBI taxonomy Id: 1630
Other names: ATCC 27783, CCUG 32236, CIP 103154, DSM 20405, K. vitulina, LMG 18931, LMG:18931, Lactobacillus vitulinus, NRRL B-14854
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.