STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfp6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (416 aa)    
Predicted Functional Partners:
SEI68041.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.982
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 0.970
SEJ20750.1
Fructose-bisphosphate aldolase, class II.
  
 
 0.936
SEI59340.1
Fructokinase.
  
 
  0.865
SEI54720.1
Transaldolase.
  
 
 0.845
SEJ04734.1
Fructose-1-phosphate kinase; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
     
 0.843
SEJ27221.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
   
 
 0.780
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
  
 
0.757
guaA
GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
   
  
 0.754
pfkA-3
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
  
  
 
0.754
Your Current Organism:
Kandleria vitulina
NCBI taxonomy Id: 1630
Other names: ATCC 27783, CCUG 32236, CIP 103154, DSM 20405, K. vitulina, LMG 18931, LMG:18931, Lactobacillus vitulinus, NRRL B-14854
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.