Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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CL1_0006Hypothetical protein containing prefoldin beta-like domain; COG0206. (97 aa)    
Predicted Functional Partners:
pfdA
Prefoldin alpha subunit 1; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
  
 0.974
pfdA-2
Prefoldin alpha subunit 2; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
   
 0.801
CL1_1145
Formate transporter; COG2116.
    
 
 0.652
CL1_0004
Hypothetical protein; COG1430.
       0.580
CL1_0168
Hypothetical protein containing peptidase M50 domain 1; COG0750.
  
  
 0.557
rpoP
DNA-directed RNA polymerase subunit P; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family.
  
  
 0.557
CL1_1582
Hypothetical protein; COG2118; Belongs to the PDCD5 family.
  
   0.536
rpl37ae
50S ribosomal protein L37Ae; Binds to the 23S rRNA.
  
  
 0.511
psmA
Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
  
 
 0.507
CL1_0816
Chaperonin subunit beta; COG0459; Belongs to the TCP-1 chaperonin family.
   
 0.468
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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