CL1_0044 protein (Thermococcus cleftensis) - STRING interaction network

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Score

CL1_0044

Riboflavin synthase subunit alpha; COG0307. (145 aa)

Predicted Functional Partners:

ribH

0.999

ribA

0.998

CL1_0045

0.974

ribK

0.900

CL1_0046

0.766

Your Current Organism:

Thermococcus cleftensis

NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CL1_0044	CL1_0045	CL1_0044	CL1_0045	Riboflavin synthase subunit alpha; COG0307.	Riboflavin biosynthesis protein RibD; COG1985.	0.974
CL1_0044	CL1_0046	CL1_0044	CL1_0046	Riboflavin synthase subunit alpha; COG0307.	Putative Prolyl oligopeptidase (preP); COG1505.	0.766
CL1_0044	ribA	CL1_0044	CL1_0043	Riboflavin synthase subunit alpha; COG0307.	GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.	0.998
CL1_0044	ribH	CL1_0044	CL1_0042	Riboflavin synthase subunit alpha; COG0307.	Putative 6,7-dimethyl-8-ribityllumazine synthase for riboflavin biosynthesis; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.	0.999
CL1_0044	ribK	CL1_0044	CL1_0129	Riboflavin synthase subunit alpha; COG0307.	Putative transcription regulator, MarR family 1; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family.	0.900
CL1_0045	CL1_0044	CL1_0045	CL1_0044	Riboflavin biosynthesis protein RibD; COG1985.	Riboflavin synthase subunit alpha; COG0307.	0.974
CL1_0045	CL1_0046	CL1_0045	CL1_0046	Riboflavin biosynthesis protein RibD; COG1985.	Putative Prolyl oligopeptidase (preP); COG1505.	0.567
CL1_0045	ribA	CL1_0045	CL1_0043	Riboflavin biosynthesis protein RibD; COG1985.	GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.	0.997
CL1_0045	ribH	CL1_0045	CL1_0042	Riboflavin biosynthesis protein RibD; COG1985.	Putative 6,7-dimethyl-8-ribityllumazine synthase for riboflavin biosynthesis; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.	0.946
CL1_0046	CL1_0044	CL1_0046	CL1_0044	Putative Prolyl oligopeptidase (preP); COG1505.	Riboflavin synthase subunit alpha; COG0307.	0.766
CL1_0046	CL1_0045	CL1_0046	CL1_0045	Putative Prolyl oligopeptidase (preP); COG1505.	Riboflavin biosynthesis protein RibD; COG1985.	0.567
CL1_0046	ribA	CL1_0046	CL1_0043	Putative Prolyl oligopeptidase (preP); COG1505.	GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.	0.514
CL1_0046	ribH	CL1_0046	CL1_0042	Putative Prolyl oligopeptidase (preP); COG1505.	Putative 6,7-dimethyl-8-ribityllumazine synthase for riboflavin biosynthesis; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.	0.434
ribA	CL1_0044	CL1_0043	CL1_0044	GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.	Riboflavin synthase subunit alpha; COG0307.	0.998
ribA	CL1_0045	CL1_0043	CL1_0045	GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.	Riboflavin biosynthesis protein RibD; COG1985.	0.997
ribA	CL1_0046	CL1_0043	CL1_0046	GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.	Putative Prolyl oligopeptidase (preP); COG1505.	0.514
ribA	ribH	CL1_0043	CL1_0042	GTP cyclohydrolase-2; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.	Putative 6,7-dimethyl-8-ribityllumazine synthase for riboflavin biosynthesis; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.	0.999
ribH	CL1_0044	CL1_0042	CL1_0044	Putative 6,7-dimethyl-8-ribityllumazine synthase for riboflavin biosynthesis; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.	Riboflavin synthase subunit alpha; COG0307.	0.999
ribH	CL1_0045	CL1_0042	CL1_0045	Putative 6,7-dimethyl-8-ribityllumazine synthase for riboflavin biosynthesis; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.	Riboflavin biosynthesis protein RibD; COG1985.	0.946
ribH	CL1_0046	CL1_0042	CL1_0046	Putative 6,7-dimethyl-8-ribityllumazine synthase for riboflavin biosynthesis; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.	Putative Prolyl oligopeptidase (preP); COG1505.	0.434