STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0056Hypothetical protein; COG0546. (219 aa)    
Predicted Functional Partners:
rbcL
Ribulose bisophosphate carboxylase; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily.
 
  
 0.934
CL1_0354
Putative phosphoglycolate phosphatase; Catalyzes the dephosphorylation of 2-phosphoglycolate.
    
 0.910
CL1_0118
2-hydroxyacid dehydrogenase-like protein; COG1052; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.905
gyaR
Glyoxylate reductase; COG1052.
    
 0.905
CL1_0055
Chromosome partitioning protein ParB-like protein; COG1475.
  
  
 0.643
hisI
Hypothetical protein; COG0139; In the N-terminal section; belongs to the PRA-CH family.
  
  
 0.551
moaA
Molybdenum cofactor biosynthesis protein A2; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
  
    0.528
CL1_1873
Hypothetical protein; COG1011.
 
   
 0.504
CL1_0824
Hypothetical protein containing Trimeric LpxA-like domain; COG0110.
  
    0.475
CL1_1342
Hypothetical protein containing HAD-like domain 7; COG0463.
 
  
0.422
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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