STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0084Translation initiation factor IF-2B subunit alpha; COG1184; Belongs to the eIF-2B alpha/beta/delta subunits family. (277 aa)    
Predicted Functional Partners:
eif2a
Translation initiation factor IF-2 subunit alpha; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-alpha family.
   
 0.867
eif2g
Translation initiation factor IF-2 subunit gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
   
 0.849
CL1_0085
Competence damage-inducible protein A; COG1058; Belongs to the CinA family.
       0.747
CL1_0109
Putative sugar-phosphate nucleotidyltransferase; COG1208.
   
 0.646
CL1_0291
Sugar-phosphate nucleotidyltransferase 1; COG1208.
   
 0.646
CL1_0414
Putative mannose-1-phosphate guanylyltransferase; COG1208.
   
 0.646
CL1_0840
Sugar-phosphate nucleotidyltransferase 2; COG1208.
   
 0.646
gap
Putative glyceraldehyde-3-phosphate dehydrogenase; COG0057.
     
 0.594
CL1_0620
Translation initiation factor Sui1; COG0023; Belongs to the SUI1 family.
   
 
 0.458
CL1_0698
DNA polymerase, family B; COG0417.
    
   0.447
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.