Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0114Hypothetical protein; COG0730. (238 aa)    
Predicted Functional Partners:
CL1_0113
Hypothetical protein; COG1100.
       0.868
CL1_0112
Hypothetical protein; COG2114.
       0.702
CL1_0116
Putative permease; COG0730.
       0.658
CL1_0111
Hypothetical protein; COG2512.
       0.652
CL1_0115
Hypothetical protein; COG0628.
       0.596
CL1_0118
2-hydroxyacid dehydrogenase-like protein; COG1052; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
       0.593
CL1_0117
Hypothetical protein containing peptidase M42 domain 1; COG1363.
       0.541
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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