STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_01182-hydroxyacid dehydrogenase-like protein; COG1052; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (333 aa)    
Predicted Functional Partners:
CL1_0354
Putative phosphoglycolate phosphatase; Catalyzes the dephosphorylation of 2-phosphoglycolate.
  
 
 0.921
gyaR
Glyoxylate reductase; COG1052.
  
  
 
0.906
CL1_0056
Hypothetical protein; COG0546.
    
 0.905
CL1_0117
Hypothetical protein containing peptidase M42 domain 1; COG1363.
       0.814
CL1_0116
Putative permease; COG0730.
       0.782
proS
prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
  
 
 0.686
CL1_1896
Pyruvate kinase; COG0469; Belongs to the pyruvate kinase family.
 
 
 0.470
CL1_1898
Amino acid transporter; COG0531.
   
 
 0.443
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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