STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0132Phosphoesterase; COG0618. (487 aa)    
Predicted Functional Partners:
dacZ
Hypothetical protein; Diadenylate cyclase that catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP is a second messenger for intracellular signal transduction involved in the control of important regulatory processes such as osmoregulation.
   
 0.648
CL1_0133
Hypothetical protein.
       0.635
CL1_0350
Hypothetical protein; COG1885; Belongs to the UPF0212 family.
  
     0.569
CL1_0168
Hypothetical protein containing peptidase M50 domain 1; COG0750.
 
     0.568
CL1_1187
DNA-binding protein, Tfx type; COG1356.
  
     0.532
CL1_0134
Putative drug/metabolite transporter 1; COG0697.
 
    0.522
CL1_1095
Hypothetical protein; COG1361.
  
     0.436
CL1_0748
Glycosyl transferase family 2 protein 2; COG0463.
 
     0.420
infB
Translation initiation factor IF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.
  
  
 0.414
CL1_1614
Chromosome segregation and condensation protein ScpA-like protein; COG1354.
 
    0.413
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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