Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CL1_0137Iron (III) ABC transporter periplasmic-binding protein; COG0614. (625 aa)    
Predicted Functional Partners:
CL1_1306
iron(III)-siderophore ABC transporter permease 2; COG0609.
 
 
 0.886
CL1_1240
iron(III)-siderophore ABC transporter permease 1; COG0609.
 
 
 0.880
CL1_1305
iron(III)-siderophore ABC transporter ATPase 2; COG1120.
 
 
 0.846
CL1_1239
iron(III)-siderophore ABC transporter ATPase 1; COG1120.
 
 
 0.815
CL1_0139
Hypothetical protein.
       0.747
CL1_0135
Putative transcription regulator containing CBS-domain; COG3620.
       0.616
CL1_0136
Hypothetical protein.
       0.583
CL1_0138
Hypothetical protein; COG0556.
       0.539
CL1_2012
Putative adenosylcobinamide amidohydrolase; COG1865.
 
  
 0.467
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
  
 0.462
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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