STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0149ABC-type transport involved in Fe -S cluster assembly, permease component; COG0719. (445 aa)    
Predicted Functional Partners:
CL1_0150
ABC-type transport involved in Fe -S cluster assembly, ATPase component; COG0396.
 
 0.999
CL1_0492
Putative cysteine desulfurase; COG0520.
 
 
 0.992
CL1_1353
Hypothetical protein; COG2151.
 
   
 0.754
CL1_1851
Cadmium-translocating P-type ATPase; COG2217.
     
 0.665
CL1_0151
Putative ATP-dependent protease Lon; COG1067; Belongs to the peptidase S16 family.
  
  
 0.585
CL1_0148
Hypothetical protein.
       0.532
CL1_1862
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
  
 0.435
CL1_0638
Glutamate synthase beta chain-related oxidoreductase containing 2Fe-2S and 4Fe-4S clusters; COG0493.
     
 0.419
infB
Translation initiation factor IF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.
     
 0.408
CL1_0152
Hypothetical protein.
       0.404
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.