STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0151Putative ATP-dependent protease Lon; COG1067; Belongs to the peptidase S16 family. (634 aa)    
Predicted Functional Partners:
CL1_1989
Chaperonin subunit alpha; COG0459; Belongs to the TCP-1 chaperonin family.
 
 
 0.705
CL1_0816
Chaperonin subunit beta; COG0459; Belongs to the TCP-1 chaperonin family.
 
 
 0.699
CL1_0998
Hypothetical protein containing peptidase M50 domain 2; COG0750.
     
 0.698
fusA
Elongation factor EF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
 
 
 0.683
CL1_0154
Metalloprotease containing JAB1/MPN domain; COG1310.
 
   
 0.669
CL1_0152
Hypothetical protein.
       0.634
CL1_1569
Small heat shock protein, Hsp20 type; COG0071; Belongs to the small heat shock protein (HSP20) family.
  
  
 0.624
CL1_0014
Hypothetical protein containing SAM domain 1; COG1244.
  
     0.607
CL1_0149
ABC-type transport involved in Fe -S cluster assembly, permease component; COG0719.
  
  
 0.585
rpl40e
50S ribosomal protein L40e; COG1552; Belongs to the eukaryotic ribosomal protein eL40 family.
  
  
  0.585
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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