STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0166Hypothetical protein; COG1786; Belongs to the UPF0107 family. (128 aa)    
Predicted Functional Partners:
CL1_0165
Hypothetical protein; COG1679.
 
 
 0.999
mvk
Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
    
  0.900
CL1_0168
Hypothetical protein containing peptidase M50 domain 1; COG0750.
       0.786
CL1_0167
Hypothetical protein; COG0438.
       0.550
rps3ae
30S ribosomal protein S3Ae; COG1890; Belongs to the eukaryotic ribosomal protein eS1 family.
 
     0.445
CL1_0336
Hypothetical protein; COG0043.
 
     0.438
CL1_0164
Homing endonucleases-like protein; COG3780.
       0.435
rps15
30S ribosomal protein S15; COG0184.
       0.418
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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