STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0240Hypothetical protein containing NADP-dependent oxidoreductase domain; COG0656. (275 aa)    
Predicted Functional Partners:
CL1_0239
Aldehyde: ferredoxin oxidoreductase 1; COG2414.
       0.916
CL1_0241
Hypothetical protein.
       0.558
CL1_0242
Transcription regulator, ArsR family 3; COG0640.
       0.558
CL1_1898
Amino acid transporter; COG0531.
  
  
 0.558
tdh
L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family.
  
 
 0.520
CL1_0826
Hypothetical protein containing oxidoreductase-domain; COG0673.
 
  
 0.497
apgM
Putative cofactor-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
       0.488
CL1_1770
Fe-containing alcohol dehydrogenase; COG1454.
   
 
 0.479
CL1_1387
Intracellular protease 1; COG0693.
 
  
 0.474
CL1_0602
Hypothetical protein; COG1422.
  
    0.472
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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