STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0249Hypothetical protein containing Histidine triad-like motif; COG0537. (169 aa)    
Predicted Functional Partners:
CL1_0673
Hypothetical protein; COG0537.
  
  
 
0.909
sat
Sulfate adenylyltransferase; COG2046; Belongs to the sulfate adenylyltransferase family.
    
 0.901
cysC
Putative adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
    
  0.901
apgM
Putative cofactor-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
       0.834
tbp
TATA-box binding protein; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.
   
 0.559
cobB
NAD-dependent deacetylase; COG0846; Belongs to the sirtuin family. Class III subfamily.
  
 
  0.545
CL1_1710
Ca2+/Na+ antiporter; COG0530.
  
    0.534
hisI
Hypothetical protein; COG0139; In the N-terminal section; belongs to the PRA-CH family.
  
    0.526
CL1_0909
Glutamine synthetase; COG0174; Belongs to the glutamine synthetase family.
  
   0.488
CL1_1475
Glucose-1-phosphate thymidylyltransferase-like protein; COG1213; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
  
 0.440
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.