STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
CL1_0274Putative pyruvate-formate lyase-activating enzyme; COG1180. (348 aa)    
Predicted Functional Partners:
CL1_0702
Hypothetical protein; COG2078.
     0.971
CL1_0570
Hypothetical protein; COG1355; Belongs to the MEMO1 family.
     0.951
CL1_0275
Hypothetical protein.
       0.916
CL1_0271
Hypothetical protein; COG0392.
       0.887
CL1_0273
Putative glycoside hydrolase/deacetylase; COG0726.
       0.887
thiL
Thiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
       0.819
CL1_0276
S-layer protein.
       0.801
CL1_0277
Hypothetical protein.
       0.775
CL1_0269
Phosphohydrolase; COG1379.
       0.769
CL1_0268
Chloride channel protein; COG0038.
       0.707
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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