Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0278Hypothetical protein; COG1031. (581 aa)    
Predicted Functional Partners:
CL1_0686
Putative thioesterase; COG2050.
       0.650
CL1_0279
Rubrerythrin-like protein 1; COG1633.
       0.572
trmY
Hypothetical protein; Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs; Belongs to the methyltransferase superfamily. TrmY family.
  
     0.519
CL1_1276
Hypothetical protein; COG0175.
  
     0.471
CL1_1736
Hypothetical protein; COG0175.
  
     0.462
CL1_0501
Putative nonsense-mediated mRNA decay protein, NMD3-family; COG1499.
  
     0.432
CL1_0880
Hypothetical protein containing SAM domain 4; COG2108.
 
     0.432
CL1_1624
Hypothetical protein; COG1833.
  
     0.417
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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