STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0289Hypothetical protein containing metallo-hydrolase/oxidoreductase domain; COG1237. (268 aa)    
Predicted Functional Partners:
CL1_0329
Dihydropteroate synthase; COG0294.
 
  
 0.928
mptE
Hypothetical protein; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP).
    
  0.901
CL1_0288
Putative GTP-binding protein; COG1084.
       0.647
CL1_0290
Hypothetical protein containing Bacitracin resistance domain; COG1968.
       0.620
CL1_0291
Sugar-phosphate nucleotidyltransferase 1; COG1208.
       0.620
CL1_0292
Hypothetical protein.
       0.620
CL1_1783
Putative dinitrogenase iron-molybdenum cofactor biosynthesis protein 1; COG1433.
 
     0.594
CL1_1790
Hypothetical protein; COG1149.
 
   
 0.570
CL1_1779
Hypothetical protein; COG1342; Belongs to the UPF0251 family.
 
     0.564
CL1_1791
Hypothetical protein; COG1149.
 
   
 0.555
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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