Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CL1_0293Hypothetical protein; COG0517. (391 aa)    
Predicted Functional Partners:
CL1_0658
Hypothetical protein; COG0517.
  
    0.844
CL1_1269
Universal stress protein 2; COG0589.
 
    0.793
rpl7ae
50S ribosomal protein L7Ae; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.
 
   0.767
rps9
30S ribosomal protein S9; COG0103; Belongs to the universal ribosomal protein uS9 family.
  
   0.752
rpl22
50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
  
 
 0.746
rpl21e
50S ribosomal protein L21e; COG2139; Belongs to the eukaryotic ribosomal protein eL21 family.
  
   0.742
rpl4
50S ribosomal protein L4P; Forms part of the polypeptide exit tunnel.
  
 
 0.740
rps2
30S ribosomal protein S2; COG0052; Belongs to the universal ribosomal protein uS2 family.
  
   0.734
rps4
30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
  
 
 0.729
rpl3
50S ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
 
 0.728
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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