STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0295Putative potassium uptake protein; COG0168. (493 aa)    
Predicted Functional Partners:
CL1_0937
Trk-type pottasium transport system, NAD-binding component; COG0569.
 
 
 0.999
CL1_0296
Cobalt transporter ATP-binding protein; COG1122.
  
  
 0.825
map
Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.
       0.641
CL1_1413
Na+/H+ antiporter; COG0025.
 
 
 
 0.444
CL1_1888
Sodium/hydrogen exchanger; COG0025.
 
 
 
 0.444
CL1_1710
Ca2+/Na+ antiporter; COG0530.
 
  
 0.422
CL1_0268
Chloride channel protein; COG0038.
 
  
 0.419
CL1_1884
Putative mechanosensitive channel; COG0668.
 
   
 0.413
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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