Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
CL1_0325AP endonuclease; COG1082. (268 aa)    
Predicted Functional Partners:
CL1_0326
Putative endopeptidase IV; COG0616.
       0.838
CL1_0327
Hypothetical protein.
       0.810
CL1_0328
Hypothetical protein; COG0628.
       0.810
CL1_0365
Bifunctional D-arabino 3-hexulose-6-phosphate formaldehyde lyase/phosphohexuloisomerase; COG0794.
 
    0.649
CL1_0332
Archeal type N-glycosylase/DNA lyase; DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- and double- stranded DNA substrates.
      
 0.618
CL1_0507
Glycosyl transferase family protein 6; COG1807.
 
    0.608
CL1_1815
CRISPR-associated protein Cas5; COG1688.
  
     0.571
CL1_0366
Putative arginase; COG0010; Belongs to the arginase family.
 
     0.567
CL1_1964
Hypothetical protein; COG1672.
  
     0.562
CL1_0839
Putative oligosaccharyl transferase, STT3 subunit 1; COG1287.
  
     0.553
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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