Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
CL1_0326Putative endopeptidase IV; COG0616. (333 aa)    
Predicted Functional Partners:
CL1_0328
Hypothetical protein; COG0628.
 
  
 0.891
CL1_0327
Hypothetical protein.
       0.875
CL1_0325
AP endonuclease; COG1082.
       0.838
CL1_0998
Hypothetical protein containing peptidase M50 domain 2; COG0750.
 
   
 0.598
ftsY
Signal recognition particle GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
 
   
 0.541
secD
Putative preprotein translocase subunit SecD; Involved in protein export.
 
   
 0.536
CL1_0168
Hypothetical protein containing peptidase M50 domain 1; COG0750.
 
   
 0.414
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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