STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CL1_0351Hypothetical protein; COG1849. (95 aa)    
Predicted Functional Partners:
CL1_0350
Hypothetical protein; COG1885; Belongs to the UPF0212 family.
       0.814
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
  
     0.537
rpl21e
50S ribosomal protein L21e; COG2139; Belongs to the eukaryotic ribosomal protein eL21 family.
 
     0.513
pyrG
CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
       0.496
CL1_0151
Putative ATP-dependent protease Lon; COG1067; Belongs to the peptidase S16 family.
  
     0.480
CL1_0499
Major facilitator superfamily permease 4; COG0477.
  
     0.475
CL1_1179
Hypothetical protein; COG1772.
  
     0.443
CL1_0646
Hypothetical protein containing metal dependent hydrolase domain; COG1831.
  
     0.424
trmY
Hypothetical protein; Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs; Belongs to the methyltransferase superfamily. TrmY family.
  
     0.419
CL1_0502
Hypothetical protein; COG2412.
  
     0.410
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.