STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurrence
Coexpression
Experiments
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[Homology]
Score
CL1_0354Putative phosphoglycolate phosphatase; Catalyzes the dephosphorylation of 2-phosphoglycolate. (245 aa)    
Predicted Functional Partners:
CL1_0118
2-hydroxyacid dehydrogenase-like protein; COG1052; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.921
gyaR
Glyoxylate reductase; COG1052.
  
 
 0.921
CL1_0056
Hypothetical protein; COG0546.
    
 0.910
rbcL
Ribulose bisophosphate carboxylase; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily.
    
  0.901
CL1_1342
Hypothetical protein containing HAD-like domain 7; COG0463.
  
 
 0.840
CL1_0353
GNAT family acetyltransferase 1; COG0454.
       0.818
truD
Putative tRNA pseudouridine synthase; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.
 
     0.732
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
       0.694
CL1_0365
Bifunctional D-arabino 3-hexulose-6-phosphate formaldehyde lyase/phosphohexuloisomerase; COG0794.
 
  
 0.666
CL1_0357
Hypothetical protein.
       0.584
Your Current Organism:
Thermococcus cleftensis
NCBI taxonomy Id: 163003
Other names: DSM 27260, KACC 17922, T. cleftensis, Thermococcus cleftensis Hensley et al. 2014, Thermococcus sp. CL1, strain CL1
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